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The low GSH concentration necessary for CVA21 displacement may also limit a co-elution of potentially bound host cell GST enzymes present in cell culture harvests, which may require as high as 10 mM GSH for elution (Figure 4A) and elution NaCl gradient (Supplementary Figure S6C) studies where CVA21 particles eluted at lower ionic strengths with increasing pH

(Its CEO says it is an advocacy organization, not a scientific one.) But the group argues the public would be safer if peptides were handled by regulated compounding pharmacies instead of the gray market

The Royal Society of Chemistry, London, pp 133

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